Fig 1: The magnetic resonance spectroscopy (MRS), IHC, and pathway validation(A–D) The MRS data show the NAA/Cr and mINS/Cr levels (four in each group, compared with Student’s t test, ∗p < 0.05).(E) The IHC figure for SEPTIN4, S1PR5, SLC5A3, and SLC5A11 in the KA rats and PBS group.(F and G) GO and KEGG analysis based on DEGs in ST data compared between moderate and severe TBI groups.
Fig 2: The link between the spatial transcriptomic and metabolites based on spatial marker genes of S1PR5 and SEPTIN4(A) The spatial expression of S1PR5 and its distribution in each sample. The red indicates the higher expression.(B) The metabolite:PC(44:7) distribution in each sample based on spatial metabolic data.(C) The spatial expression of SEPTIN4 and its distribution in each sample. The red indicates the higher expression.(D) The metabolite:aspartic acid distribution in each sample based on spatial metabolic data.
Supplier Page from Abcam for Anti-EDG8 antibody - N-terminal